Scientists have not identified the cause of endometriosis so different theories exist. Shedding from the endometrium is a natural part of your period. But not all cells flow out the cervix. During this process, endometrial cells also flow through your fallopian tubes and settle in the pelvic area. Normally the immune system should clean these out. Because of a possible failure of immune system function, the endometrial cells may attach to the tissues in the pelvis. Cyclic bleeding in endometriosis then causes worsening cramps due to inflammation of the surrounding tissue.

Another theory of endometriosis is preprogrammed cell transformation. Some researchers feel the menstrual fluid induces this cell transformation.

Endometriosis tends to run in families, which supports a potential genetic link.

Endometriosis is stimulated by cyclic ovarian estrogen and progesterone production, so symptoms generally subside after menopause. HRT (estrogen with progesterone) for menopause may result in pain.

The most common symptoms of endometriosis we see at the Advanced Women’s Institute include:

• Worsening menstrual cramps
• Increased days of cramping in the cycle
• New painful intercourse
• Cyclic bowel and/or urinary pain
• Nonspecific bowel and/or urinary pain
• Lower back pain
• Pelvic pressure

There are two main choices for managing endometriosis, medical or surgical, and both have their merits. Options for medical management include:

• Oral contraceptives (OCs): Generally the first recommendation, especially for younger women. OCs reduce menstrual cramps and flow. Side effects, complications, failure to control pain or return of symptoms may occur. It is possible to give OC’s continuously to extend the interval between periods, thus decreasing periods to 4 or less each year. It doesn’t work for every woman, but is worth a try.
• Progestin IUD: An IUD that releases progestin can reduce or stop the period which help menstrual pain of endometriosis. They are not as effective for non-menstrual pain or pain with intercourse.
• Pain medication: Non-Steroidal Anti-Inflammatory drugs such as ibuprofen can help cramps. This is also a first line treatment and is frequently combined with OCs. Narcotic pain medication can also be used but there is concern about the risk of opioid addiction.
• Progestins: Progestins bind inside the ovary to reduce estrogen production and prevent ovulation. There are oral and injectable(Depo) formulas. Side effects include depression symptoms and abnormal bleeding. Progestins are relatively inexpensive.
• GNRHa (gonadotropin releasing hormone agonist): A class of compounds that selectively stop the pituitary gland from stimulating the ovaries. They are highly effective. The estrogen levels can get so low some women develop hot flashes and night sweats common to menopause. They are also costly.
• GNRH antagonists: They lower estrogen like the agonist, only faster. The side effect profile and patient tolerance is similar to the GNRHa.

There are a variety of medicines available, each with their own side effects. Dr. Moore and the team will discuss each option with you in detail. It should be kept in mind that drug treatment does not cure endometriosis, but continuous use of your medication can help you manage your symptoms effectively. For more permanent solutions, you may opt for a surgical solution, such as:

• Sclerotherapy for endometrioma: This is an in-office procedure to eliminate the endometriosis inside the cyst. The endometrioma cyst disappears. Sclerotherapy can help reduce pain and avoid surgery. It also is less damaging than cystectomy.
• Laparoscopy: This requires small incisions in the abdomen so a scope can be inserted through the belly button to diagnose and treat endometriosis. If endometriosis is identified at the time of diagnostic laparoscopy, an operative laparoscopy can then be performed to remove the endometrial tissue implants. This requires additional small incisions for the placement of graspers, scissors, and other instruments to remove the implants. The procedure is done as an outpatient and return to work is expected in approximately 2 weeks or less.
• Open Abdominal Surgery for Endometriosis: This procedure is accomplished using a 4-6 inch open abdominal incision to perform the operation. However, laparoscopy represents a less invasive, less painful approach to endometriosis, and is preferable.

There are two surgical solutions, conservative reproductive surgery and permanent hysterectomy surgery.

• Conservative: Endometriosis is treated without removal of organs. Excisional therapy has been shown to be more effective for pain than ablative therapy. We will make sure you go to the right surgeon for you.
• Permanent: Hysterectomy is sometimes the most effective way to help the pain of endometriosis. We will discuss all conservative options as long as it is important to avoid this permanent solution.

Medical and surgical management have been studied scientifically. Some other ways to help manage endometriosis pain include:

• Heating pad, hot bath, Epsom salt bath can help pain temporarily
• Acupuncture, studies indicate it may help relieve pain temporarily but not long term
• Massage Therapy and self-massage studies indicate temporary but not sustained pain relief
• Rieki is touted for pain relief but lacks scientific support
• Naturopathic medicine is not proven but would not harm, may be costly
• Chinese herbs similarly may help but are not proven and cost may also be an issue
• Herbs such as Tumeric, Pine Bark, Chamomile, Peppermint, Willow Bark, Vitex(Chaste Berry) and Ashwagandha have been reported to help pain but are still controversial

It may be possible to manage some symptoms with various alternative methods. Although controversial, it does not hurt to try them. Cost may be the only issue.