I: PERSONAL DATAName: Michael L. MooreDate of Birth: September 30, 1955Place of Birth: McAllen, Texas, USACitizenship: United States of AmericaOffice Address: 210 University Blvd, Suite 500Denver, CO 80206Office Telephone: 303 – 321 – 2255 Fax: 303 – 321 – 0856E:Mail AWHIDenver@aol.comMarital Status: June 27, 1981 (Donnis)Children: Lenzy, September 4, 1984II: EDUCATIONB.S. University of Oklahoma (Summa cum Laude)Norman, Oklahoma, 1977M.D. University of Oklahoma College of MedicineOklahoma City, Oklahoma, 1981Residency: Gynecology and ObstetricsUniversity of Oklahoma Health Sciences CenterOklahoma City, Oklahoma, 1981 – 1985Board Certification Obstetrics and GynecologyAmerican Board of Obstetrics and GynecologyDecember, 1989
Advanced Laparoscopic and Hysteroscopic SurgeryAccreditation Council of Gynecologic EndoscopyDecember, 1995CPR – American Heart Association – June 1999-2001- American Red Cross, July 2001 – 2002- American Safety and Health Institute September 2003-2005The International Society for Clinical DensitometryCertified Clinical Densitometrist (C.C.D.)September, 10, 1999 – September 10, 2005Training: The International Society for Clinical DensitometryCertification Course, Santa Fe, NW August 4/5 2002III: PROFESSIONAL EXPERIENCELicensure: State of Oklahoma #13880, July 1982 (not current)State of Colorado #27296, January, 1986Appointments: Assistant Clinical Professor,University of Colorado Health Sciences CenterDenver, Colorado 1986 – presentDiplomat, American Board of Obstetrics and Gynecology, 1988 – presentFellow, American College of Obstetrics and Gynecology, 1991 – presentEditorial Advisory Board,Conceive Magazine, 1989 – 1991Sanofi-Wintrhrop Speakers Bureau, 1993 – 1996Parke-Davis speakers Bureau, 1993 – 1999Chairman, Dept. OB/GYNAvista Hospital, Louisville, CO 1997-1998Co-director,Porter-Littleton Advanced Endoscopic Training Center, Littleton, CO 1997-1998Clinical FacultyThe Advanced Training Institute for Gynecologic Health, 1998-1999Medical DirectorAdvanced Women’s Health InstituteDenver, Colorado 1999 – presentConsultantGynecare, Sommerville, New Jersey1999 – presentFellowship Director,Advanced Gynecologic Endoscopic SurgeryAAGL-SRS2000 – 2004Private Practice: Southern Plains Medical CenterChickasha, Oklahoma 7/15/85 to 1/25/86Reproductive Associates4500 East Ninth Avenue, Suite 630 Denver, CO 80220 1/30/86 to 1993Conceptions Reproductive Associates4500 East Ninth Avenue, Suite 630 Denver, CO 80220 1993-1999Advanced Women’s Health Institute 210 University Blvd, Suite 500Denver, CO 80206 1999-presentProfessional Organizations: American Medical AssociationColorado Medical SocietyDenver Medical SocietyColorado Gynecological and Obstetrical SocietyAmerican Association of Gynecologic LaparoscopistsAmerican Society of Reproductive Medicine
Honors: Phi Eta SigmaPhi Beta KappaAyerst Award for “Outstanding Paper” 1984Resident Research PresentationGolden Minisite Award “Best Microendoscopy Paper”American Association of gynecologic Laparoscopist29th Annual Meeting, November 2000, Third Prize Moore ML, Cohen M: Diagnostic transvaginal hydrolaparoscopy (THL) and operative transvaginal hydrolaparoscopy (OPTHL) for infertility and pelvic pain, American Association of Gynecologic
Kurt Semm Award, “Excellence in Pelviscopy” American Association of gynecologic Laparoscopist29th Annual Meeting, November 2000, Second PrizeMoore ML, Cohen M: The evolution of the Moore laparoscopic hysteroplasty (MLH), an effective alternative to hysterectomy for women with fibroids and menorrhagiaJerome Hoffman award for “Best Postgraduate Paper” American Association of Gynecologic Laparoscopists 30th Annual Meeting, November 15-21st, 2001, second prizeLiu GY, Moore ML, Cohen M: Assessment of 104 laparoscopic supracervical hysterectomiesIV: RESEARCH GRANT:Coculture of Human Embryos with Bovine Oviductal Cells. Growth in the Presence or Absence of Commercially Prepared Basement Membrane, Rose Foundation, 1993 – $ 50,000.V: EDUCATIONAL GRANTS:Fellowship in Advanced Endoscopic Surgery, 2000-2001, Gynecare Corporation, confidentialFellowship in Advanced Endoscopic Surgery, 2001-2002, Gynecare Corporation, confidentialVI: CLINCAL RESEARCH EXPERIENCES:Principal Investigator:Double-Blind, Randomized, Active-Controlled Protocol Comparing a Study Drug Patch to Oral Estrogen in the Treatment of Vasomotor Symptoms of Postmenopausal Women.Principal Investigator:Double-Blind, Randomized, Placebo-controlled Assessment of an Estradiol/Levonorgestrel Containing Patch for the Treatment of Vasomotor Symptoms of Postmenopausal Women.Principal Investigator: 1998Double-Blind, Randomized, Placebo-Controlled Trial of an Estradiol/Levonorgestrel Containing Patch to Evaluate the Endometrium of Women on Postmenopausal Hormone Replacement Therapy.Principal Investigator: October 1999Cryo-Ablation Reduction of MENstruation (CARMEN): Soprano Cryotherapy System
Principal Investigator: 1998A multi-Center, Randomized, Placebo-Controlled, Double Blind, Dose-Ranging Study to Assess the Effect of INS-1 on Insulin and Ovarian Androgen Production in Obese Women with Polycystic Ovarian Syndrome (PCOS)Principal Investigator:A Multi-center, comparison of Continuous Transdermal Estradiol-Levonorgestrel Combinations, Examining the Effect on the Endometrium and Bleeding Patterns in Previously Randomized Postmenopausal Women who Have Completed 13 cycles (1 year) of Estradiol-Levonorgestrel hormone Replacement therapy.Principal Investigator: May 2000Evaluation of the Thermachoice II UBT SystemPrincipal Investigator: October 2000Laser Heating of the Endometrium vs. Rollerball endometrial Ablation for the Treatment of Excessive Uterine Bleeding, Randomized Trial No. R2K/06Principal Investigator: May 2002A Phase III, 12 Month, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety (including Bone Density Assessment) of two Doses of J867 Versus placebo in Subjects with Uterine Leiomyomata. Protocol No. MO1-390Principal Investigator: November 2003A Phase III, 12 Month, Extension Study to Evaluate the Safety of Asoprisnil in Subjects with Uterine Leiomyomata. Protocol No. MO1-391Principal Investigator: July 2003A Phase III, 6 Month, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of two Doses of Asoprisnil Versus Placebo in Subjects with Uterine Leiomyomata. Protocol No. CO2-037Principal Investigator March 2004A Phase 3, 18 Month, Extension Study to Evaluate the Safety of Asoprisnil in Subjects with Uterine Leiomyomata. Protocol No. C03-062Principal Investigator September 2004A Randomized clinical trial comparing the Smith and Nephew Operative Hysteroscopy System to Loop Resectoscopy Protocol 55-OHS-04Principal Investigator December 2004A Phase 3, Continuation Study to Evaluate the Long Term Safety of Asoprisnil in Subjects with Uterine Leiomyomata Protocol AFB-04-078Principal Investigator March 2005A Phase II, Randomized, Double Blind, Placebo-controlled, Multi-center Study to Evaluate the Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients with Interstitial Cystitis Protocol MN-001-CL-002Principal Investigator March 2005Comparison of the Safety and Efficacy of a Unique Intravenous Iron Preparation (Vit-45) versus Oral Iron in the Treatment of Iron Deficiency Anemia Secondary to Heavy Uterine Bleeding Protocol 1VIT04002Principal Investigator July 2005A Phase 1, 6 Month, Randomized, Double-Blind, Placebo-Controlled Study of the Effects of Asoprisnil on Ovarian Activity and Ovulation in pre-Menopausal Subjects Protocol NO C02-038Sub-Investigator:A Study to Assess Safety and Efficacy of Tibolone, a Drug for Endometrial Protection in Postmenopausal Women given Oral conjugated Estrogen Replacement Therapy.Sub-Investigator:Comparison of Albunex Sonohysterography to Radiographic Hysterosalpingography in the Evaluation of the Fallopian Tube for Patency and Pathology.Sub-Investigator:Multi-Centered, Randomized, Double-Blind, Placebo-Controlled Dose to Evaluate the Efficacy and Safety of an Investigational Medication in the Prevention of Osteoporosis in Postmenopausal Women.VII: SCIENTIFIC INTERESTSInfertilityEndoscopic SurgeryTransvaginal SonographyDysfunctional Uterine BleedingTransvaginal HydrolaparoscopyBIBLIOGRAPHYPublicationsMoore ML, A persepective on GIFT, Conceive Magazine, Vol.1, no.3., p.16, 1989.Bell H, Garcia RB, Albrecht BH, Gottesfeld RL, Worley RJ, Moore ML: Refrigerated Storage of Ham’s F10 Culture Medium in Assisted Reproduction Programs. Journal of Assisted Reproduction and Genetics: 112:750-754, 1995.Moore ML: Transvaginal Hydrolaparoscopy: Preliminary Assessment of Cost-Effectiveness. Gynetrenes: Advanced Endoscopic Techniques, Vol 3, No 1, September 1999.Moore ML, Cohen M: Diagnostic Transvaginal Hydrolaparoscopy (THL) and Operative Transvaginal Hydrolaparoscopy (OPTHL) for Infertility and Pelvic Pain, J. Am Assoc Gynecol Laparosc., 8(3):393-397, 2001.Moore ML, Minimally Invasive Surgery for Women I, Zenith Woman, 5(3),16, 2001Moore ML, Minimally Invasive Surgery for Women II, Zenith Woman, 5(4), 26, 2001Moore ML, Cohen M: Experience with 109 cases of Transvaginal Hydrolaparoscopy (THL), J. Am Assoc Gynecol Laparosc., 10(2):282-285, 2003Video PublicationsTransvaginal Sonography, General electric Diagnostics, contributor, 1989.Laser Safety, Baxter Hospital Supply, contributor, 1988.OPERASL: Hysteroscopic Surgery In Physiologic Distention Media. FemRX Corporation, contributor and faculty, 1997.AbstractsMoore ML, Thurneau Grace Liu, M.D., Kling OR: In vitro placental production of thryomboxane A2 and prostacyclin I2 in severe preclampsia. Society for Gyneoclogic Investigation, 32nd Annual Meeting, pg. 154.Moore ML, Howe SE: A comparison of enzyme immunoassay and immunobead test for antisperm antibodies. American Fertility Society, 44th Annual Meeting, Abst. P-0001.Moore ML, Hepner HJ: A comparison of diagnostic laparoscopy and pelvic sonography with enhanced acoustic interface. American Fertility Society 44th Meeting, Abst P-0119.Moore ML, Hepner HJ: Danzaol as an adjuvant to management of suspected ectopic and persistent trophoblast after conservative surgery. American Fertility Society 44th Annual Meeting, Abst. P-130Albrecht BH, Garcia RB, Bell H, Gottesfeld RL, Worley RJ, Moore ML, Longevity of human sperm is increased over conventional culture when cocultured with bovine oviductal cells. Conjoint Meeting, American Fertility Society and Canadian Andrology Society, Montreal, October, 1993.Garcia RB, Albrech BH, Moore ML, Worley RH: ICSI as therapy for persistent polyspermic fertilization of oocytes: report of a case. American Society for Reproductive Medicine, Boston Massachusetts, November, 1996.
Olive DI, Kresch AJ, Feste JR, Lotze EC, Moore ML, Bertrand J, Savage GM: The OPERASTAR SL: A new device for hysteroscopic electrosurgery in physiologic distention media. International Society of Gynecologic Endoscopists, Meeting, 1997.Wexler P, Albrecht BH, Moore ML, Worley RJ, Strates E: Infertility, Recurrent pregnancy loss and chromosomal abnormalities. The American Journal of Human Genetics, Volume 63, Number 4, October, 1998.Moore ML, Albrecht BH, Worley RJ, Strates E, Cohen, M: Comparison of total laparoscopic myomectomy with laparoscopic assisted myomectomy. American Association of Gynecologic Laparoscopists 27th Annual Meeting, Atlanta, GA, November 10-15, 1998.Moore ML, Cohen, M: Laparoscopic myomectomy using a power morcellator for in-situ multiple myomectomy in women undergoing concurrent endometrial ablation. American Association of Gynecologic Laparoscopists 28th Annual Meeting, Las Vegas, Nevada, November 8-11, 1999.Moore ML, Cohen M: In-office transvaginal hydrolaparoscopy (THL) for the evaluation of pelvic anatomy in the infertile women. American Society of Reproductive Medicine Annual Meeting, San Diego, California, 2000.Moore ML, Burke GV, Surrey MW, Cohen M: Transvaginal hydrolaparoscopy (THL) for the evaluation of pelvic anatomy in the infertile women, a review of the initial experience in the United States. American Society of Reproductive Medicine Annual Meeting, San Diego, California, 2000.Moore ML, Cohen M: Diagnostic transvaginal hydrolaparoscopy (THL) and operative transvaginal hydrolaparoscopy (OPTHL) for infertility and pelvic pain, American Association of Gynecologic Laparoscopists 29th Annual Meeting, Orlando, Florida, November 14-19, 2000.Moore ML, Cohen M: The evolution of the Moore laparoscopic hysteroplasty (MLH), an effective alternative to hysterectomy for women with fibroids and menorrhagia, American Association of Gynecologic Laparoscopists 29th Annual Meeting, Orlando, Florida, November 14-19, 2000.Cohen M, Moore ML, Liu GY: Comparison of Monopolar and Biopolar endometrial resection ablation for abnormal uterine bleeding, American Association of Gynecologic Laparoscopists 30th Annual Meeting, San Francisco, California, November 15-21, 2001.Cohen M, Moore ML, Liu GY: Comparison of Office and Hospital endometrial resection ablation for abnormal uterine bleeding, American Association of Gynecologic Laparoscopists 30th Annual Meeting, San Francisco, California, November 15-21, 2001.Liu GY, Moore ML, Cohen M: Assessment of 104 laparoscopic supracervical hysterectomies, American Association of Gynecologic Laparoscopists 30th Annual Meeting, San Francisco, California, November 15-21, 2001.Liu GY, Moore ML, Cohen M: Office Diagnostic Transvaginal Hydrolaparoscopy with Oral Analgesia to Evaluate Primary Infertility, American Association of Gynecologic Laparoscopists 30th Annual Meeting, San Francisco, California, November 15-21, 2001.Moore ML, Cohen M, Liu GY: Experience with 109 Cases of Transvaginal Hydrolaparoscopy, American Association of Gynecologic Laparoscopists 30th Annual Meeting, San Francisco, California, November 15-21, 2001.Moore ML, Cohen M, Liu GY, Waliser TJ: Transvaginal Hydrolaparoscopy for evaluation of infertile women, American Association of Gynecologic Laparoscopists 31st Annual Meeting, Miami Beach, Florida, November 20-24, 2002.Waliser TJ, Cohen M, Moore ML: Laparoscopic myomectomy, American Association of Gynecologic Laparoscopists 31st Annual Meeting, Miami Beach, Florida, November 20-24, 2002.Cohen M, Waliser TJ, Moore ML: Risk of contracting HIV and Hepatitis for obstetric-gynecologic surgical health care providers, American Association of Gynecologic Laparoscopists 31st Annual Meeting, Miami Beach, Florida, November 20-24, 2002.Moore ML, Cohen, M: A dedicated Gyn surgery unit has a better outcome for outpatient laparoscopic supracervical hysterectomy(LSH) than a general outpatient surgery facility. American Association of Gynecologic Laparoscopists 32nd Annual Meeting, Las Vegas, Nevada, November 19-22, 2003.Brown T, Moore ML, Cohen M: A Seven Year Operative Laparoscopy Experience in Private Practice. American Association of Gynecologic Laparoscopists 33 rd Annual Meeting, San Francisco, California, November 10-14, 2004.Video AbstractsMoore ML, Hepner HJ: Pelvic sonography with enhanced acoustical interface. American Fertility Society, 44th Annual Meeting.Moore ML, Cohen M: Operative transvaginal hydrolaparoscopy for the treatment of minimal or mild endometriosis. American society of Reproductive Medicine, Annual Meeting, San Diego, California, 2000.Cohen M, Moore ML: Endometrial ablation in physiologic solution using the gynecare versapoint resectoscope system, American Association of Gynecologic Laparoscopists 29th Annual Meeting, Orlando, Florida, November 14-19, 2000.Cohen M, Moore ML: Operative transvaginal hydrolaparoscopy for the treatment of minimal or mild endometriosis, American Association of Gynecologic Laparoscopists 29th Annual Meeting, Orlando, Florida, November 14-19, 2000.Moore ML, Cohen M, Liu GY: Outpatient laparoscopic supracervical hysterectomy, American Association of Gynecologic Laparoscopists 30th Annual Meeting, San Francisco, California, November 15-21, 2001.