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Advance Women's
Health Institute
Michael L. Moore, M.D.

425 S Cherry St
Suite 907
Denver, CO 80246
USA

Office: 303.321.2255
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Fax: 303.321.0856


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Hormone Therapy

How do I take hormone replacement therapy?

What about natural estrogens?

How do I take hormone replacement therapy?
If you have a uterus:
Continuous combined - Estrogen and progesterone everyday
Continuous sequential - Estrogen everyday, and progesterone for part of the cycle
Cyclic combined - Estrogen and progesterone everyday, then a break from both
Cyclic sequential - Estrogen every day, then a break, and progesterone for part of the cycle, then a break

If no uterus:
Estrogen only and continuously, no need for progesterone

Consider transdermal estrogen if:
High triglycerides
Gallbladder disease
Migraine headaches
GI upset
Compliance problems
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What about natural estrogens?
Phytoestrogens, also known as isoflavones are very weak estrogen agonists, and work best when there is little circulating estradiol to compete with for receptor sites.
Diet:
Phytoestrogens are contained in soy food products, flax seed and some legumes. Asian diets have about 10 times the amount of phytoestrogens as the average American diet, and it has been suggested that because of this Asian women have fewer hot flashes, hip fractures, and hormone dependent cancers than American women.

In all areas of postmenopausal health, more blinded randomized controlled trials are needed to look at the actual benefit.
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